Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy
Summary: Galactose (Gal)-deficient IgA1 (Gd-IgA1) is involved in IgA nephropathy (IgAN) pathogenesis.To reflect racial differences in clinical peperomia double duty characteristics, we assessed disease- and race-specific heterogeneity in the O-glycosylation of the IgA1 hinge region (HR).We determined serum Gd-IgA1 levels in Caucasians (healthy cont